Both of your comments have been pinned as they add crucial information. Feel free to extract anything you want from this article, repost it, share it, squirrel it off, post another article. Mine is more intended as a major highlighter for the reproductive harms that media seem to have missed; I don't have the required specialisms to dive into the chemical complexities or biological interactions further.
The "N" in 3-nitrooxypropanol got me thinking about metabolites, such as N-nitrosamines, which have loooong been associated with cancer. It's why we were told not to eat too much bacon, etc.
***
Induction of liver tumors in Wistar rats by sodium nitrite given in pellet diet
Which is why nitrite formation as a breakdown metabolite of Bovaer presents "a bit of a problem".
The fix is simple. Redefine nitrites as safe, and no longer linked to cancer 🤞👌🤫
***
Nitrites are now safe again
... An oxidant called 3-nitrooxypropanol (3-NOP, aka Bovaer) binds to the active site of MCR and oxidizes an essential SH group, inhibiting production of methane in bacteria. The effect only lasts for 5 hours at a concentration of 1 μM,[7] after which the bacteria reactivate the enzyme. 3-NOP is rapidly absorbed by the intestine and makes its way through the animal's bloodstream, and is then denitrated in the liver. This probably explains why 100× more 3-NOP is needed to produce the effect in the animal than in cultured bacteria. 3-NOP is metabolized to nitrate, nitrite, and 1,3-propanediol.
Absolutely excellent and relevant insight, pinned.
And yes, there are cancer associations. Several outlets have covered or pointed to the cancer aspect, however to my knowledge *none* have covered the reproductive harms, hence my near sole focus on that topic.
Cancer is mentioned in the form of hyperplasia (mesenchymal cell hyperplasia):
“Based on this finding of mesenchymal cell hyperplasia in males at 100 mg/kg bw/day, the NOAEL was concluded to be 50 mg/kg bw/d”
I strongly suspect people will believe the title of this article is either too strong or clickbait, but having assessed the fact the evidence of fertility is a *known harm* and is *publicly visible in broad daylight*, being *proactively covered up*, only governments wishing to intentionally cause harms would approve and mandate this product whilst attempting to cover-up the harms.
Any device used to intentionally cause harm is called a weapon. Any device that reduces or negates or harms fertility is an anti-fertility device. Ergo, this is a literal anti-fertility weapon. The only way the title could be stronger is if I explicitly stated governments are waging war on fertility, which would not be an unreasonable assertion, however I think it is necessary to explicitly call out "Bovaer" for exactly what it is.
Ask DSM-Firmenich why they won't give this feed to bulls.
The multihit theory of cancer. In isolation in small amounts from food each of these Bovaer type agents may not be highly carcinogenic, but in combination they may work synergistically and you should try to limit exposure.
Think teflon, BPAs, glyphosate, Al etc
They should also never be approved in the first place.
"... Cancer is known to result primarily from genetic mutations [1–3]. Moreover, models of carcinogenesis–the multi-stage and multi-hit models–suggest that cancer results from a small number of (two–seven) mutations [4–11]."
Related to 'stacked effects' is polyethylenimine (transfectant) and polyethylene glycol (allergen inducer). The latter of which is part of Bovaer's ingredient make-up.
Is there no limit to which the corrupt 'Establishment' will not go to undermine humanity?
Strangely, 'Bovaer' seems to be another of Bill Gates's surreptitious plans to smuggle poisons into the human food chain. Boycot Arla products unless the packaging confirms 'NO Bovaer'!
Another Gates product is Apeel which is a poisonous coating that supposedly slows down the deterioration of fresh fruit and vegetables. This material remains on the skins and cannot be washed off. Whether it permeates the skin is as yet unknown! Beware!
There is already a high awareness that Arla products are unsafe - if not population-reducing. We must raise awareness of all food products using this formulation to facilitate planet depopulation. Please check all grocery for these poisons being used in or on the foods you buy.
Gates recently bought a Dutch ARTIFICIAL MEAT company called Picnic. Who knows what is contained in this 'food source'?
Beware of all ARLA products and boycott them if they include any materials that might be harmful to humans as they could reduce the population by causing infertility.
By now you should recognise that we are in a war for survival. No more jabs, Bovaer or Arla!
Unjabbed Mick (UK) We'll live longer by avoiding mRNA-laced injections.
Another must see is this science memo from New Zealand (2022).
The regulators put Bovaer as GHS Category 2 for reproductive toxicity.
(It's worse still for rats).
***
... The EPA considers that the mechanism of toxicity is not sufficiently characterised to enable a firm
conclusion that the toxicity to the testis and epididymis is a rat specific finding but does suggest that
other species may be less sensitive to the compound. Therefore, the EPA does not consider that it
can be concluded that this finding has no human relevance. Consequently, the clear evidence of an
adverse effect on reproduction in a combined toxicity screening study in the absence of other toxic
effects, supported by evidence from repeat dose studies showing the male reproductive organs to be
the target organs for toxicity justifies classification for reproductive toxicity. The EPA concludes that
the appropriate classification is GHS Category 2 for reproductive toxicity.
https://www.google.co.uk/url?sa=t&source=web&rct=j&opi=89978449&url=https://www.epa.govt.nz/assets/FileAPI/hsno-ar/APP204100/APP204100-Science-Memo-Final.pdf&ved=2ahUKEwi13dyMhLeKAxWYQUEAHVixJw4QFnoECBcQAQ&usg=AOvVaw3vrxcW6687mcstvafc9aHm
Both of your comments have been pinned as they add crucial information. Feel free to extract anything you want from this article, repost it, share it, squirrel it off, post another article. Mine is more intended as a major highlighter for the reproductive harms that media seem to have missed; I don't have the required specialisms to dive into the chemical complexities or biological interactions further.
The "N" in 3-nitrooxypropanol got me thinking about metabolites, such as N-nitrosamines, which have loooong been associated with cancer. It's why we were told not to eat too much bacon, etc.
***
Induction of liver tumors in Wistar rats by sodium nitrite given in pellet diet
M Aoyagi et al. J Natl Cancer Inst. 1980 Aug.
https://pubmed.ncbi.nlm.nih.gov/6931259/
***
Which is why nitrite formation as a breakdown metabolite of Bovaer presents "a bit of a problem".
The fix is simple. Redefine nitrites as safe, and no longer linked to cancer 🤞👌🤫
***
Nitrites are now safe again
... An oxidant called 3-nitrooxypropanol (3-NOP, aka Bovaer) binds to the active site of MCR and oxidizes an essential SH group, inhibiting production of methane in bacteria. The effect only lasts for 5 hours at a concentration of 1 μM,[7] after which the bacteria reactivate the enzyme. 3-NOP is rapidly absorbed by the intestine and makes its way through the animal's bloodstream, and is then denitrated in the liver. This probably explains why 100× more 3-NOP is needed to produce the effect in the animal than in cultured bacteria. 3-NOP is metabolized to nitrate, nitrite, and 1,3-propanediol.
https://randombio.com/nitrite.html
Absolutely excellent and relevant insight, pinned.
And yes, there are cancer associations. Several outlets have covered or pointed to the cancer aspect, however to my knowledge *none* have covered the reproductive harms, hence my near sole focus on that topic.
Cancer is mentioned in the form of hyperplasia (mesenchymal cell hyperplasia):
“Based on this finding of mesenchymal cell hyperplasia in males at 100 mg/kg bw/day, the NOAEL was concluded to be 50 mg/kg bw/d”
https://www.food.gov.uk/print/pdf/node/16051
Another quote might spook you further:
“the Panel concluded that 3‐NOP can induce chromosome damage through a clastogenic mechanism of action”
https://pmc.ncbi.nlm.nih.gov/articles/PMC8603004/
So yes, very much a cancer aspect.
"Clastogenic" = mutagenic= chromosome breaks & rearrangement.
The war on food continues
I strongly suspect people will believe the title of this article is either too strong or clickbait, but having assessed the fact the evidence of fertility is a *known harm* and is *publicly visible in broad daylight*, being *proactively covered up*, only governments wishing to intentionally cause harms would approve and mandate this product whilst attempting to cover-up the harms.
Any device used to intentionally cause harm is called a weapon. Any device that reduces or negates or harms fertility is an anti-fertility device. Ergo, this is a literal anti-fertility weapon. The only way the title could be stronger is if I explicitly stated governments are waging war on fertility, which would not be an unreasonable assertion, however I think it is necessary to explicitly call out "Bovaer" for exactly what it is.
Ask DSM-Firmenich why they won't give this feed to bulls.
Maybe "Bovaer is mass sterilization"
🎯
The multihit theory of cancer. In isolation in small amounts from food each of these Bovaer type agents may not be highly carcinogenic, but in combination they may work synergistically and you should try to limit exposure.
Think teflon, BPAs, glyphosate, Al etc
They should also never be approved in the first place.
"... Cancer is known to result primarily from genetic mutations [1–3]. Moreover, models of carcinogenesis–the multi-stage and multi-hit models–suggest that cancer results from a small number of (two–seven) mutations [4–11]."
https://pmc.ncbi.nlm.nih.gov/articles/PMC6424461/
Related to 'stacked effects' is polyethylenimine (transfectant) and polyethylene glycol (allergen inducer). The latter of which is part of Bovaer's ingredient make-up.
https://thedailybeagle.substack.com/p/the-transfectant-agent-found-in-your
#Bovaer
Take a guess at the class 1 confirmed carcinogen that just led to this recall:
FDA Updates Recall On Blood Pressure Medication Due To Possible Carcinogen
https://www.zerohedge.com/medical/fda-updates-recall-blood-pressure-medication-due-possible-carcinogen
Is there no limit to which the corrupt 'Establishment' will not go to undermine humanity?
Strangely, 'Bovaer' seems to be another of Bill Gates's surreptitious plans to smuggle poisons into the human food chain. Boycot Arla products unless the packaging confirms 'NO Bovaer'!
Another Gates product is Apeel which is a poisonous coating that supposedly slows down the deterioration of fresh fruit and vegetables. This material remains on the skins and cannot be washed off. Whether it permeates the skin is as yet unknown! Beware!
There is already a high awareness that Arla products are unsafe - if not population-reducing. We must raise awareness of all food products using this formulation to facilitate planet depopulation. Please check all grocery for these poisons being used in or on the foods you buy.
Gates recently bought a Dutch ARTIFICIAL MEAT company called Picnic. Who knows what is contained in this 'food source'?
Beware of all ARLA products and boycott them if they include any materials that might be harmful to humans as they could reduce the population by causing infertility.
By now you should recognise that we are in a war for survival. No more jabs, Bovaer or Arla!
Unjabbed Mick (UK) We'll live longer by avoiding mRNA-laced injections.
Climate culls, frankenfoods, animal 'vaccination' - all basically bioweapons to livestock and humans.
part of the transhumanist agenda... https://eccentrik.substack.com/p/transhumanism-is-the-extermination