Midazolam, Opioids, And How To Treat Them

For doctors and public out there still with a heart

Disclaimer: The Daily Beagle is a Citizen Journalism outlet, and we cannot give medical advice, so it is best to speak with a medical professional. Nor is this legal advice, speak with a legal professional. This is purely for informational purposes only.

If you’ve read Mass Murdering Of The Elderly or The Death Penalty Drugs Used By Care Homes, you may have become disheartened about Midazolam and similar toxic drugs, feeling once administered, death is final.

But it turns out, not so! There are two drugs that can help combat both the use of Benzodiazepines (E.G. Midazolam) and Opioids (E.G. Morphine), the lethal combo.

Medical professionals should be aware of these, but in-case there are any who aren’t, or have forgotten, we’re raising these options to attention, so any with heart may help reverse mass murdering of the elderly.

One drug — Naloxone — can, in emergency circumstances, be administered by members of the public in the UK!

Flumazenil

Also known as ‘Flumazepil’, ‘Anexate’, ‘Romazicon’ and ‘78755-81-4’ (molecular formula C15H14FN3O3), it is a imidazo-benzodiazepine derivative, it is an antidote to benzodiazepines, particularly in overdose situations.

Administrators of the drug need to be aware that it has a shorter half-life (7 to 80 minutes) than Midazolam (1.5 to 2.5 hours) and similar benzodiazepines, and thus likely will require repeat administrations to ensure effectiveness maintains for the half-life duration of Midazolam and similar benzodiazepines.

In the UK, Flumazenil has BNF code 1501070F0, Anexate has BNF code 1501070F0BB.

They share a similar BNF code with Naloxone Hydrochloride, 1501070G0AA. However Naloxone serves a different but equally as useful purpose.

Naloxone

Also known as ‘Narcan’, ‘l-Naloxone’, ‘n-Allylnoroxymorphone’, and in the UK ‘Prenoxad’, ‘Nyxoid’, it is listed in the US with number ‘465-65-6’ (molecular formula C19H21NO4), a synthetic morphinane alkaloid, a thebaine derivate, and acts as a opiate antagonist, counteracting the effects from opioid overdoses rapidly.

Naloxone has BNF code 1501070G0, Prenoxad has code 1902070Q0BD, and Nyxoid code 1902070Q0BE. Nyxoid is a nasal spray, Prenoxad and Naloxone are injectable.

UK Is Surprisingly Flexible On Naloxone

In the UK, Naloxone can be given without a prescription; the UK also permits drug services to provide those suffering an opioid overdose without express permission, quoting:

[…] it is legal for a drug service to provide a family member or friend of a heroin or opioid user with naloxone without the express permission of the person who is using the heroin or opioid […]

To say, grandma or grandpa does not need to be conscious, nor give consent to receive counteracting Naloxone from a drug service, obtainable without prescription, in the UK. Any heroic drug services who wish to save lives can do this.

For lay folk, ‘drug service’ here, likely means ‘trained medical professional who knows how to correctly administer an injection’ (E.G. NHS staff member, pharmacist, care worker, etc).

They need not be the same drug service as the one supplying Naloxone. E.G. you could get Naloxone from one drug service (E.G. pharmacist), and have another drug service (E.G. nurse) administer the shot.

That said, the UK government does state:

However, in an emergency, anyone can use any available naloxone to save a life.

Including:

a carer, a friend, or a family member of a drug user at risk

So even if you cannot find a drug service willing to save a life, in an emergency, hypothetically speaking, you can. Speak with a lawyer for legal details.

Those concerned about injectability or their lack of skills, should be aware in the UK there is a nasal formulation (that would be Nyxoid):

Both injectable and nasal formulations are available.

So if inexperienced with injections, asking for a nasal formulation would be likely the most sensible precaution.

Hopefully readers can forgive us for not publishing a doom-and-goom news story for today, and we hope this will be used to help save lives in this mass murder machine.

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