Assessing 898 COVID-19 Shot Studies: Studies #12 to #22
Assessing 898 COVID-19 Shot Studies: Studies #12 to #22
59.2% increase post-shot in pericarditis, dubious consensus advice, and post-mortem findings
If you haven’t already, see our previous article "Assessing 898 COVID-19 Shot Studies: Studies #1 to #11".
12. Perimyocarditis following first dose of the mRNA-1273 SARS-CoV-2 (Moderna) vaccine in a healthy young male: a case report
The temporal [time] aspect of this case is close that it’s not even attributable to anything else. As established before, perimyocarditis means both pericarditis and myocarditis have the same cause.
Had COVID-19 with six months of no consequences. Three days after taking the Moderna shot develops chest pains. Emphasis added:
An 22-year-old Caucasian male presented to our hospital center complaining of pleuritic chest pain. Six months prior he had a mild case of COVID-19, but was otherwise healthy. He had received his first dose of the Moderna vaccine three days prior to developing symptoms.
The conclusion of the study is pretty straight forward, although it tries to speculate on the probability of risk without the data to back it up: if you’ve only examined one case, how do you know it is rare?:
We present a case of perimyocarditis that was temporally related to COVID-19 mRNA vaccination in an young male with prior COVID-19 infection but otherwise healthy. Our case report highlights an albeit rare but important adverse event for clinicians to be aware of. It also suggests a possible mechanism for the development of myocardial injury in our patient.
13. Secondary immune thrombocytopenia supposedly attributable to COVID-19 vaccination
Thrombocytopenia - enia meaning ‘without’, thrombocyte (from thrombocyto) a type of cell (cyte) responsible for thrombosis (clotting). That is to say, the patient had no clotting cells, meaning if they were injured, they wouldn’t stop bleeding.
Here, we report a case of secondary ITP in a patient who was recently immunised with the messenger RNA COVID-19 vaccine BNT162b2 (Pfizer–BioNTech).
ITP is short for ‘Immune thrombocytopenic purpura’, and looks like this:
ITP is caused by autoimmunity, which the study notes can be triggered by shots, or in this case, the Pfizer mRNA shot.
14. Immune thrombocytopenic purpura and acute liver injury after COVID-19 vaccine
Like study #13 above, study #14 also includes a reference to ITP, but tacks on acute liver damage as well:
A 26-year-old woman was sent to the emergency room by her primary care physician for a new petechial rash and thrombocytopenia 2 weeks after receiving the Moderna mRNA-1273 SARS-CoV-2 vaccine. Her hospital course was complicated by transaminitis. Her platelet count improved to normal on hospital day 5 after receiving intravenous steroids and intravenous immunoglobulin to treat her suspected diagnosis of immune thrombocytopenic purpura.
A petechial rash is tiny purple/red/brown spots on the skin, which compared to the image above, is what you’d expect to see in ITP. Thrombocytopenia we already know means ‘without clotting cells’. Steroids suppress the immune system and inflammatory response, and ‘intravenous immunoglobulin’ would be a blood transfusion of antibodies.
Transaminitis is what indicates the liver damage. ‘itis’ means ‘of’ or ‘pertaining to’ and typically means an inflammation. It refers to high levels of liver enzymes called transaminases, and usually indicates damage to the liver itself. A bad sign.
15. Effects of surgical and FFP2/N95 face masks on cardiopulmonary exercise capacity [Not Relevant]
It is interesting amongst the 898 studies on COVID-19 shots, there is one on masks. It isn’t relevant to the subject criterion on COVID-19 shots they were presented under, however.
16. Acute myocarditis associated with anti-COVID-19 vaccination
This study’s title is particularly weirdly worded. What they mean is “vaccination” is “anti-COVID-19”, not that people who are opposed to COVID-19 shots are getting acute myocarditis. Such a bizarre, confusing choice of words. In-fact, the unusual wording continues:
Novel anti-coronavirus disease 2019 mRNA vaccines are rapidly implemented worldwide.
The study notes that in three males, that diffuse ST elevations were shown in ECGs (electrocardiograms), and lab tests showed raised inflammatory markers and myocardial enzymes.
Myocardial edema (swelling, fluid retention) was shown, I think the study means ‘via gadolinium enhancement’ (which is a cardiac magnetic resonance technique, not an injury), although the way the study words it, it makes it sound like the patient has gadolinium enhancement, which is a bit like saying one of your symptoms is ‘blood test’:
[…] but myocardial edema and gadolinium enhancement of the myocardium were evident in cardiac magnetic resonance imaging, confirming the diagnosis of myocarditis
The study also notes in the images there is “inflammatory necrosis” of the heart.
Given it is an Israeli study, I suspect the mangled wording is due to translation issues.
17. Petechial skin rash associated with CoronaVac vaccination: first cutaneous side effect report before phase 3 results
As we already know, a petechial rash is tiny purple/red/brown spots on the skin. Cutaneous just means ‘relating to the skin’.
CoronaVac is the Chinese COVID-19 shot developed by Sinopharm, and more common outside western countries. The study was conducted in Istanbul.
It reports that a woman developed a rash 1 day after receiving the Sinopharm shot. The testing was fairly thorough, and included tests for HIV antibodies, C-reactive protein, D-dimer tests and more.
The study interestingly references another document of interest, remarking that the rashes wouldn’t develop “if prednisolone was <20 mg”. Prednisolone is an anti-inflammatory steroid. It has little to do with what is likely an ITP case given the symptoms (the study doesn’t diagnose it as ITP).
What’s curious is they refer to the American College of Rheumatology’s study “COVID-19 Vaccine Clinical Guidance Summary for Patients with Rheumatic and Musculoskeletal Disease”
However, there are several problems with this citation. Firstly, the document is a ‘living’ document, in that it constantly changes and gets updated in real time, meaning whatever was cited historically, may not be there any longer, making it a bad citation source for a study.
The newer document doesn’t reference this claim, but the archived version does:
It is odd that Rheumatology is being used for guidelines on COVID-19 shot safety. Re-quoting the Istanbul study again:
[…] when safety in vaccine effect was reported if prednisolone was <20 mg […]
And yet the evidence for this claim wasn’t peer reviewed. Notice the above image shows “consensus”? This isn’t how peer-review works, and no evidence was provided by American College of Rheumatology to back up their claims, no datasets, no evidence, no case studies, nothing. And then the newer document scrubs it all like it never even happened. Another prime example of terrible medical practice, corrupt even.
This is extremely alarming that medical practitioners are taking advice from liquid, unsubstantiated PDF documents simply because of the name of the organisation that sits at the top of the page is a well known one.
18. A Prothrombotic Thrombocytopenic Disorder Resembling Heparin-Induced Thrombocytopenia Following Coronavirus-19 Vaccination [Pre-Print]
This is a pre-print study, meaning this specific linked study hasn’t been peer-reviewed, however, the page refers to an updated, peer-reviewed study.
I will be updating it to the peer-reviewed version:
Thrombotic Thrombocytopenia after ChAdOx1 nCov-19 Vaccination
ChAdOx1 is the AstraZeneca shot, nCov-19 is the classic name for SARS-CoV-2. Interestingly the differences between the titles is large. Prothombotic has been replaced with thrombotic, and ‘resembling Heparin-Induced’ has been removed.
Summarising the results page:
11 patients, 9 women, ranging between 22 to 49 years old
Occurred within 5 to 16 days of receiving the shot
1 patient died of fatal intracranial hemorrhage
9 had cerebral venous thrombosis (which is what the EMA leak warned about!)
3 had splanchnic-vein thrombosis
3 had pulmonary embolism
4 had thrombosis
5 patients had disseminated intravascular coagulation
6 patient died
This is pretty damning, a whole slew of fatal injuries, of which are so numerous in just 11 patients that it has to be presented as a bulletpointed list. The most notable one is the “cerebral venous thrombosis”, which is what the EMA leak warned about in the ‘Janssen shot’ (Janssen manufacture shots for Johnson & Johnson, and is the same technology used in AstraZeneca).
The publicly available conclusion notes that it mimics autoimmune heparin-induced thrombocytopenia:
Vaccination with ChAdOx1 nCov-19 can result in the rare development of immune thrombotic thrombocytopenia mediated by platelet-activating antibodies against PF4, which clinically mimics autoimmune heparin-induced thrombocytopenia.
19. Post-mortem findings in vaccine-induced thrombotic thombocytopenia
Thrombotic thombocytopenia also produces thrombotic thombocytopenia purpura (TTP), which is basically the same thing as immune thrombocytopenic purpura (ITP).
The study remarks that:
The main macroscopic finding was that venous thrombosis was much more widespread and catastrophic than diagnosed by imaging during life.
Venous here means ‘in/of the veins’, and thrombosis, again, means clotting. Clotting in the veins.
The study title also highlights another dark aspect: “post mortem”. Mort is Latin for the word ‘death’, and post means ‘after’. So, ‘after death’. The examination is being performed after the person has died. The study remarks that the thrombosis was in “unusual sites”:
[…] two fatal cases of venous thrombosis located in unusual sites are similar to those recently described […]
It remarks that internal brain bleeding was the cause of death. Note that because this is also thrombocytopenia (without clotting cells), it would have led to internal bleeding.
Venous thrombosis was accompanied by severe intracranial bleeding, which was the final cause of death in both
The reason they lacked clotting cells to deal with the internal bleeding is because the clotting cells were being ‘used up’ elsewhere to cause clotting in the veins.
20. Myocarditis and Pericarditis After Vaccination for COVID-19
The study reinforces the short duration between receiving the shot and myocarditis/pericarditis, remarking:
Myocarditis occurred a median of 3.5 days (IQR, 3.0-10.8 days) after vaccination […]
The study notes a higher rate of pericarditis after the second shot rather than the first:
Pericarditis developed after the first immunization in 15 cases […] and after the second immunization in 22 cases […]
With a higher rate in mRNA shots than genetically modified adenovirus shots (Ad26 - adenovirus type 26), with Pfizer being the worst contender compared to Moderna:
mRNA-1273 vaccine, 12 cases [32%]; BNT162b2 vaccine, 23 cases [62%]; Ad26.COV2.S vaccine, 2 cases [5%]
mRNA-1273 - Moderna shot.
BNT162b2 - Pfizer/BioNTech shot.
Ad26.COV2.S - Janssen/Johnson & Johnson shot.
The study goes on to note that the mean number of cases of myocarditis or myopericarditis (myocarditis and pericarditis) was 16.9 cases pre-shot, and 27.3 post-shot, a rise of 10.4, showing a clear increasing trend caused by the shots:
The mean monthly number of cases of myocarditis or myopericarditis during the prevaccine period was 16.9 (95% CI, 15.3-18.6) vs 27.3 (95% CI, 22.4-32.9) during the vaccine period (P < .001)
Pericarditis by itself had a whopping leap in numbers in contrast, noting it was a mean of 49.1 cases pre-shot, leaping to a whopping 78.8 post-shot, meaning a massive increase of 29.1 cases, basically a 59.2% increase!
The mean numbers of pericarditis cases during the same periods were 49.1 (95% CI, 46.4-51.9) and 78.8 (95% CI, 70.3-87.9)
The study goes on to declare there is an adverse harms underreporting:
This study shows a similar pattern, although at higher incidence, suggesting vaccine adverse event underreporting […]
21. Association of Receipt of the Ad26.COV2.S COVID-19 Vaccine With Presumptive Guillain-Barré Syndrome, February-July 2021
Relates to the Johnson & Johnson/Janssen shot. This a study flagging up an early warning based on underreported VAERS data about GBS increases in Johnson & Johnson/Janssen shots:
These findings suggest a potential small but statistically significant safety concern for Guillain-Barré syndrome following receipt of the Ad26.COV2.S vaccine but are considered preliminary pending analysis of medical records to establish a definitive diagnosis.
22. Myocarditis Occurring After Immunization With mRNA-Based COVID-19 Vaccines
Reports 4 myocarditis cases in mRNA shots - 2 for Moderna, 2 for Pfizer, in which the key events occurred after the second shot, within the short timeframe of 1 to 5 days:
The first report describes 4 cases of myocarditis with symptom onset 1 to 5 days after receipt of a second dose of mRNA-based COVID-19 vaccine (2 receiving the BNT162b2-mRNA vaccine and 2 receiving the mRNA-1273 vaccine)
They also report 23 cases from military health which were within ‘4 days’ of mRNA shots.
The second, larger case report comes from the US Military Health System and describes 23 individuals with acute myocarditis who presented within 4 days after mRNA-based COVID-19 vaccination
It is worth bearing in mind, military members have to be in peak physical condition in order to continue serving in the military, undergoing regular health examinations, so if they had any prior health issues they would have already been removed from service, so the sole attributable cause here are the shots.
As the study notes, 22 of the 23 were on “active duty”, reinforcing they were previously in peak physical health:
All patients were male, 22 of 23 were on active duty […]
The study goes on to declare - quite predictably - that despite a search for alternative causes (“etiologies”), none were found, and the only common ground was the mRNA shots:
The striking clinical similarities in the presentations of these patients, their recent vaccination with an mRNA-based COVID-19 vaccine, and the lack of any alternative etiologies for acute myocarditis suggest an association with immunization.
Prior article: "Assessing 898 COVID-19 Shot Studies: Studies #1 to #11".
If you like this work, be sure to subscribe!
Or help share our hard work with other people!
Seen something? Leave a comment!
You are doing exceptional work, Underdog! Hats off to you!